Key features
- Up to 24 parallel flow experiments
- Precise shear force control (0 – 200 dyn/cm2)
- Pulsatile flow (0-1.2 Hz at 20 dyn/cm2; 0-72 bpm)
- Includes Zeiss microscope with customisable accessories and camera
- Software for automatic flow and microscope control, image acquisition and analysis
- Applications: Antimicrobial & mutant screening, Atherosclerosis modeling, Biofilm adhesion & growth, Cell movement, Host-pathogen interactions, Platelet adhesion & aggregation, Transmigration, etc.
Sales in
Austria, Belgium, Denmark, Finland, France, Germany, Ireland, Luxembourg, Norway, Sweden, Switzerland, The Netherlands, United Kingdom
BioFlux 1000HT: The Ultimate Turnkey Solution
The BioFlux 1000HT is the ultimate shear flow system for laboratories requiring complete flexibility and advanced imaging capabilities. This high-throughput platform allows researchers to conduct complex, physiologically relevant shear flow assays with unparalleled precision. Designed for versatility, the BioFlux 1000HT offers a fully customisable microscope, shear control, and user-defined image capture and software analysis, enabling researchers to tailor the system to their specific needs.
Supporting applications such as platelet aggregation studies, host-pathogen interaction assays, and drug discovery experiments, the BioFlux 1000HT excels at bridging the gap between in vitro and in vivo research. Its advanced features, including e.g. temperature control, an automated motorised stage, and six fluorescence channels, ensure accurate and reproducible results. With this fully customisable solution, your lab can push the boundaries of shear flow research and uncover new biological insights.
Consumables
| FL-910-0110-5 | BioFlux 1000HT 6-well plates, 0-20 dyn, Qty 5 |
| FL-910-0051-5 | BioFlux 1000HT 24-well plates, 0-20 dyn, glass bottom, Qty 5 |
| FL-910-0145-5 | BioFlux 1000HT 24-well plates, 0-20 dyn, PDMS bottom, Qty 5 |
| FL-910-0047-5 | BioFlux 1000HT 48-well plates, low shear, 0-20 dyn, Qty 5 |
| FL-910-0048-5 | BioFlux 1000HT 48-well plates, high shear, 0-200 dyn, Qty 5 |
| FL-910-0120-5 | BioFlux 1000HT 48-well plates, custom substrate bottom Qty 5 |
| FL-910-0121-5 | BioFlux 1000HT 48-well plates, 0-20 dyn, PDMS bottom, Qty 5 |
| Accessories | |
| FL-200-0031 | BioFlux harness, from controler to vapor trap |
| FL-200-0032 | BioFlux harness, from vapor trap to 48-well interface |
| FL-200-0033 | BioFlux harness, from vapor trap to 6- or 24-well interface |
| FL-300-0008 | BioFlux filter 0.2 µM luer lock for contr.+vapor trap pk. 2 |
| FL-800-0068 | BioFlux gasket for 24-well interface |
| FL-800-0069 | BioFlux gasket for 48-well interface |
| FL-800-0072 | BioFlux gasket for 6-well interface |
| FL-910-0017 | BioFlux filter 0.2 µM luer lock replacement filters pk. 10 |
| FL-900-0115 | BioFlux 1000HT 6-well plate interface cover |
| FL-930-0242 | BioFlux 1000HT stage insert, without heater |
| FL-950-0059 | BioFlux 1000HT stage insert with heater |
| FL-950-0029 | BioFlux 1000HT 24-well Interface cover |
| FL-950-0030 | BioFlux 1000HT 48-Well Interface cover |
| FL-930-0266 | Stage mounting frame to hold well plates/ large petri dishes |
| FL-930-0267 | Stage mounting frame to hold slides/ small petri dishes |
| Further accessories on request |
Downloads
BioFlux Brochure
Bioflux Overview Poster
Application Note: Growth of environment-specific biofilms using the BioFlux system
Application Note: Pseudomonas aeruginosa growth on airway epithelial cells
Flyer: Compare the Bioflux 200 and 1000 systems
Compare the two systems and see which shear flow system is meeting your needs to mimic in-vivo biology
Technical data
| Flow control | 0 – 200 dyn/cm2 Dual flow control, bi-directional |
| Pulsatile flow | Frequence: 0 – 1.2 Hz at 20 dyn/cm2 (0-72 bpm) |
| Environmental control | Dual gas input. Variable gas composition, e.g. premixed CO2. Physical/temporal gradients, Hypoxia. Temperature control possible with heating stage from ambient up to 50°C |
| Microtiterplates | SBS Standard, pre-sterilised, with PDMS channels and glass/PDMS/custom substrate bottom |
| Microtiter plate format | 6-well for up to 3 long-term experiments (1 inlet well/ channel) |
| 24-well for up to 8 experiments (2 inlet wells/ channel) | |
| 48-well for up to 24 experiments (1 inlet well/ channel) | |
| Throughput | Up to 24 experiments in parallel |
| Observation channel | Dimensions: 350 µm (width) x 70 µm (height) Parallel microscopable channels/experiments per viewing window: 48-well: 2; 24-well: 4; 6-well: 2 and 1 |
| BioFlux Controller dimension | 30 x 33 x 23 cm |
| Weight | approx. 17 kg (BioFlux controller) |
| Microscope | Automated Zeiss microscope with motorized Z-Drive and Nosepiece, individually equipped. More details on request. |
| Software | BioFlux software; Montage Plus software combines BioFlux shear flow and microscope control and imaging analysis |
| BioFlux 1000HT system | Includes BioFlux 200+ controller with BioFlux control software, vapor trap, heater electronics, accessory kit, dual gas capability, environmental control, and pulsatile flow. Individually equipped (heating) stage and quick connector interfaces and Zeiss microscope with computer workstation, Montage Plus software etc. |
