Key features
- Up to 24 flow experiments in parallel
- Precise shear force control (0 – 200 dyn/cm2)
- Automatic flow control, pulsatile flow
- 48/24 well plate formats with PDMS microchannels with glass, PDMS or custom substrate bottoms
- Compatible with most inverted microscopes
- Applications: Platelet adhesion & aggregation, Biofilm formation, Cell movement, Host-pathogen interactions, etc.
Sales in
Austria, Belgium, Denmark, Finland, France, Germany, Ireland, Luxembourg, Norway, Sweden, Switzerland, The Netherlands, United Kingdom
BioFlux 200+: Affordable Shear Flow for Any Lab
The BioFlux 200+ is an accessible, flexible solution designed to integrate seamlessly into your existing laboratory setup. Compatible with most inverted microscopes, it empowers researchers to conduct physiologically relevant shear flow experiments with ease. Ideal for laboratories aiming to replicate in vivo conditions, the BioFlux 200+ delivers precision, high-throughput capabilities, and unmatched versatility.
This system allows you to analyse up to 24 independent samples per plate, making it perfect for applications such as biofilm growth studies, platelet adhesion & aggregation assays, and cell migration research. Assays can be easily customised using single or dual-flow microfluidic channels, constant or pulsatile flow, and with wall shear stresses ranging from 0 to 200 dyn/cm². Dual gas inputs, temperature control, and user-friendly software ensure a streamlined workflow while maintaining experimental accuracy. For labs seeking cost-effective innovation, the BioFlux 200+ is the perfect entry point into shear flow experimentation.
Consumables
| FL-910-0004-5Pack | BioFlux 200+ 48-well plates, low shear, 0-20 dyn, Qty 5 |
| FL-910-0033-5Pack | BioFlux 200+ 48-well plates, high shear, 0-200 dyn, Qty 5 |
| FL-910-0115-5Pack | BioFlux 200+ 48-well plates, 0-20 dyn, PDMS bottom, Qty 5 |
| FL-910-0119-5Pack | BioFlux 200+ 48-well plates, custom substrate bottom, Qty 5 |
| FL-910-0050-5Pack | BioFlux 200+ 24-well plates, 0-20 dyn, glass bottom, Qty 5 |
| FL-910-0116-5Pack | BioFlux 200+ 24-well plates, 0-20 dyn, PDMS bottom, Qty 5 |
| Accessories | |
| FL-950-0031 | BioFlux 200+ 24-well Interface |
| FL-950-0032 | BioFlux 200+ 48-well Interface |
| FL-950-0034 | BioFlux 200+ Heating Stage |
| FL-200-0031 | BioFlux harness vapor trap, from controller |
| FL-200-0032 | BioFlux harness vapor trap to 48-well interface |
| FL-200-0033 | BioFlux harness vapor trap to 6/24-well interface |
| FL-300-0008 | BioFlux filter 0.2 uM luer lock for controller and vapor trap pk. 2 |
| FL-800-0068 | BioFlux gasket for 24-well interface |
| FL-800-0069 | BioFlux gasket for 48-well interface |
| FL-910-0017 | BioFlux filter 0.2 uM luer lock replacement filters pk. 10 |
| Further accessories on request |
Downloads
BioFlux Brochure
Bioflux Overview Poster
Application Note: Growth of environment-specific biofilms using the BioFlux system
Application Note: Pseudomonas aeruginosa growth on airway epithelial cells
Flyer: Compare the Bioflux 200 and 1000 systems
Compare the two systems and see which shear flow system is meeting your needs to mimic in-vivo biology
Technical data
| Flow control | 0 – 200 dyn/cm2 Dual flow control, bi-directional |
| Pulsatile flow | Frequence: 0 – 1,2 Hz at 20 dyn/cm2 (0-72 bpm) |
| Environmental control | Dual gas input. Variable gas composition, e.g. premixed CO2. Physical/temporal gradients, Hypoxia. Temperature control possible with heating stage from ambient up to 50°C |
| Microtiterplates | SBS Standard, pre-sterilised, with PDMS channels and glass/PDMS/custom substrate bottom |
| Microtiter plate format | 24-well for up to 8 experiments (2 inlet wells/ channel) |
| 48-well for up to 24 experiments (1 inlet well/ channel) | |
| Throughput | Up to 24 experiments per plate |
| Observation channel | Dimensions: 350 µm (width) x 70 µm (height) Parallel microscopable channels/experiments per viewing window: 48-well: 2; 24-well: 4 |
| Controller dimension | 30 x 33 x 23 cm |
| Weight | approx. 17 kg |
| Microscope | Not included – Compatible with inverted microscopes with a minimum working distance of 6 cm between stage and condenser |
| BioFlux 200+ system | Includes controller with BioFlux control software, vapor trap, heater electronics, accessory kit, dual gas capability, environmental control, and pulsatile flow. The accessory kit includes power supply for controller, pressure gauge, tubing and fitting for single gas use, and torque wrench for interface connection to plates. (Heating stage and interfaces seperately available.) |
