Key features
- Generate 10–20 times more viable monoclonal colonies in weeks instead of months, lowering the cost per clone.
- Cultivate single cells in a flask-like setting without physical separation, preserving cell physiology and viability.
- Effortlessly and delicately isolate CellRafts with cells or colonies of interest, without relying on fluidics.
- Capture image-based documentation to verify monoclonality.
Sales in
France, Ireland, Italy, United Kingdom
CellRaft AIR® System: The Next Generation Technology for Faster Activation & Cloning of Single Cells
The CellRaft AIR® System is an integrated, high-viability single-cell culture, automated imaging, and isolation platform. Using unique CellRaft® technology, it maintains cells in their physiologic state to enable more effective clonal expansion without the requirement for aggressive fluidics or trypsinisation.
The system features label-free brightfield imaging and fluorescence analysis for real-time tracking of cell growth and morphology, which facilitates the continuous detection of monoclonal colonies. A magnetic wand-based isolation process non-disruptively extracts intact clones while maintaining viability for subsequent cell line development, CRISPR editing, and organoid applications.
- Generate 10-20× more viable monoclonal colonies in weeks, not months, with reduced costs per clone.
- A culture environment resembling a plastic flask allows cell growth without physical separation, preserving internal physiology.
- Selection-based, fluidics-free, and automated isolation of individual CellRafts enables gentle, contamination-free processing.
- OCR-based tracking supports regulatory documentation at scale and streamlines workflows.
Utilizing a combination of high-throughput imaging, software-guided intelligent selection, and automated isolation, the CellRaft AIR® System delivers the fastest workflows without compromising cell viability and clonality – enabling researchers to produce greater clones in less time.
Consumables
| CM-CS-CAL | CellRaft® AIR – Calibration Array |
| CM-CS-100Q | CellRaft® Array, 100 micron wells with a quad reservoir, single unit |
| CM-CS-100Q-5 | CellRaft® Array, 100 micron wells with a quad reservoir, pack of 5 |
| CM-CS-100S | CellRaft® Array, 100 micron wells with a single reservoir, single unit |
| CM-CS-100S-5 | CellRaft® Array, 100 micron wells with a single reservoir, pack of 5 |
| CM-CS-200Q | CellRaft® Array, 200 micron wells with a quad reservoir, single unit |
| CM-CS-200Q-5 | CellRaft® Array, 200 micron wells with a quad reservoir, pack of 5 |
| CM-CS-200S | CellRaft® Array, 200 micron wells with a single reservoir, single unit |
| CM-CS-200S-5 | CellRaft® Array, 200 micron wells with a single reservoir, pack of 5 |
| CM-CS-500S | CellRaft® Array, 3D, 500 micron wells with a single reservoir, single unit |
| CM-CS-500S-5 | CellRaft® Array, 3D, 500 micron wells with a single reservoir, pack of 5 |
Downloads
Brochure
Learn more on the CellRaft technology and how it can be used to sort and isolate cells at the same time.
Streamlined single B cell screening
Unlock rapid antibody discovery with CellRaft Technology, screen 80,000 single B cells in one run, preserving native pairing and accelerating your research.
Poster - Antibody discovery, screening and production using CellRaft® techology.
The CellRaft AIR System offers a more direct approach, enabling earlier identification of relevant clones and reduced reliance on bulk screening workflows.
Application note - Restoring high-titer antibody production in a hybridoma cell line.
Restore high-titer antibody production in hybridoma lines in under a month using CellRaft Technology to isolate rare, high-producing clones with precision.
Case Study - High Efficiency Cell Line Development of a Density-Dependent Hepatic Cell Line
Academic researchers used CellRaft Clone Challenge Technology to generate true monoclonal Hep3B hepatoma populations for studying hypoxia induced gene expression.
Application Note - Accelerate Cell Line Development by Isolating Monoclonal Colonies, Not Single Cells
This application note describes how CellRaft Technology outperforms traditional limiting dilution by isolating monoclonal colonies from challenging cell lines.
Case Study - Accelerating the Development of In Vitro Models of Chemoresistance.
To uncover mechanisms of chemoresistance in Ewing’s sarcoma, UNC Chapel Hill researchers exposed two cell lines to common chemotherapeutics. Limiting dilution failed to yield monoclonal populations, so they turned to CellRaft Technology for reliable single-cell cloning.
Transforming How Organoids are Grown and Isolated.
Learn more on how the CellRaft Technology with 3D capabilities offers a solution with a fully automated imaging, analysis, and isolation workfl ow for organoid culture.
Poster - Accelerating the use if iSPC-derived organoids in drug discovery and personalized medicine.
This poster describes the experimental work performed to demonstrate that CellRaft Technology provides streamlined, reproducible organoid workflows that offer reliable imaging, software-guided selection, and automated isolation of single organoids for downstream applications.
Technical data
| Imaging | |||
| Channel | Representative dyes | Excitation | Emission |
| Blue | DAPI, Hoechst | 379 – 401 nm | 412 – 453 nm |
| Green | FITC, GFP | 461 – 489 nm | 498 – 548 nm |
| Red | mCherry, Texas Red | 559 – 591 n | 603 – 805 nm |
| Specifications | |||
| Size | 20” High, 20” Deep, 27” Wide | ||
| Weight | 125 lbs | ||
| Camera | 2752 x 2192 resolution (6MP) 4.54 x 4.54 µm pixels 8-bit depth |
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| Magnification | 1.2 x 1.4 mm field of view 0.57 µm/pixel* *On par with 20X magnification using a typical scientific microscopy camera |
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| Computer and Monitor | Included | ||
| Data Storage | 0.5 TB on computer, 0.5 TB external USB drive, network capable (ethernet, wi-fi) |
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| Stage Top Incubator | Optional | ||
| Power | 125/250 VAC, 10A, 60/50 Hz | ||
| Certification | ISO 61010, FCC emissions, CE Mark |
