CF1 and CF2 Cell Disruptor

Constant Systems Ltd.

High pressure cell disruption - research to production

The high-pressure homogenizers from Constant Systems Ltd. enable efficient and reproducible lysis of various cell types – such as E. coli and very robust organisms like yeasts, algae and gram-positive bacteria. The product range offers solutions for smaller research experiments up to applications in larger production plants.

CF1 CF2 CS-TS Gebogener-Auslass

Key features

  • Free selectable pressure range up to 2700 bar (40 kpsi)
  • Continuous sample processing at the push of a button
  • Robust technology with limited maintenance needs
  • No air pressure installation necessary, just an electrical connection
  • Efficient cooling of the processed sample with an optional chiller
  • Automatic Stop after 3 shots of air

Sales in

Austria, Belgium, Germany, Luxembourg, Switzerland, The Netherlands

CF1 and CF2 High-pressure homogenizer

The CF models homogenize cell suspensions continuously with the principle of high pressure relief (known as French-Press-principle). In a free selectable pressure range up to 2700 bar (40 kpsi) all kind of cell suspensions are processed and efficiently disrupted: bacteria, yeast, algae, mammalian and insect cells, fungus etc.. Even at the highest pressure proteins are not denatured, that is why this technology is very beneficial and mostly used for protein isolation. This model is designed for applications in research, development and analytics.

The model CF1 with 1.1 kW compressor power is the smaller table variant and processes sample volumes at a speed of 100 ml/min. Automatic sample supply and hydraulic cooling are optionally available.

For processing even larger volumes, the free-standing model CF2 is available with a process speed of 400 ml/min (24 l/h) and a compressor output of 4 kW.

Viscous samples need the alternative HAIVA model option, which can be built in all four compression versions. These systems have disruption head with an enlarged inlet area for clumpy or high viscous samples, e.g. filamentous fungus or plant cell cultures.

Downloads

CF brochure

Main brochure

CF paper

Technical data

CF1 Cell Disruptor

Process volume max 10 L
Dead volume 1 mL (0.3-0.5 mL with OneShot Head Adapter OSHA)
Minimal volume 10 mL (1mL with OSHA)
Cycles 100 mL/min
Pressure up to 2700 bar (40.000 PSI)
Sample type liquid (all states with OSHA)
Fixed orifice yes
Sample cooling yes (optional)
Compressed air required no
Dimensions (H x W x D) 74 x 70 x 62.5 cm
Weight 110-130 kg
Add ons peristaltic process pump, oil cooling circuit
Optional extras OSHA, trolley

CF2 Cell Disruptor

Process volume max 100 L
Dead volume 2 mL (0.3-0.5 mL with OneShot Head Adapter OSHA)
Minimal volume 15 mL (1mL with OSHA)
Cycles 405 mL/min
Pressure up to 2700 bar (40.000 PSI)
Sample type liquid (all states with OSHA)
Fixed orifice yes
Sample cooling yes. Integrated
Compressed air required no
Dimensions  (H x W x D) 134 x 70 x 72 cm
Weight 240 kg
Add ons peristaltic process pump integrated
Optional extras OSHA