Automated high density cell culture system

Manufacturer: Parker Hannifin

The MabTec® high density cell culture system is a fully automated gravimetric bioreactor maintenance system. Its capabilities include automated feed, harvest or recirculation in fully disposable or hybrid bioreactor flow paths. The system also includes the ability to conduct unattended bioreactor inoculations, bolus feed and/or pump flow reversals (to prevent filter fouling) all on one unit with run times from hours to months.
The MabTec is available with a choice of pump heads and can feed bioreactor sizes from 50 mL to 2000 L. The MabTec is engineered to fit seamlessly with any bioreactor and enhance its performance.
A laboratory scale, available separately, must be connected to use the MabTec’s gravimetric features.


Features and Benefits:

  • Safe, walk-away system operation
  • Maintains a steady state bioreactor weight / volume within +/- 0.5%
  • Real-time data collection with optimization tools
  • Small, lightweight and mobile
  • Works with any bioreactor
  • Eliminates bioreactor addition errors
  • Reduces aggregation of cells in the perfusion filter
  • Intuitive application interface
  • Flow rates from 0.03 ml/min to 2258 ml/min (depending on configuration)
  • Operational modes: perfusion, re-circulation, feed: 2 scales, feed: 1 scale, seed induction, manual


  • Pressure sensores: Accommodates three SciPress pressure sensors (included). The calibration range is 0 – 60 psi. Any point within this range can be recalibrated using an external pressure reference source
  • Motor/Encoder: 8, 160, 600 rpm, 30 VDC, 3.8 A
  • I/O ports:
    •       Male DB9 scale connector
    •       Female DB9 printer or PC connector
    •       External IO DB37 connector 4 TTL input
    •       3x 4 – 20 mA analogue input: constant rate/ constant pressure filtration 
    •       with user-definable alarms
  • Enclosure: 16 Ga, aluminium baked epoxy blue
  • Dimensions: 5.75” x 8.5 “ x 11” (15 cm x 22 cm x 28 cm)
  • Weight: 14 lbs (6.4 kg)
  • Power: 115/220-240 VAC, 60/50 Hz

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