Semi-Automated NFF and TFF Systems for Pilot Plant and Small Scale Production

Manufacturer: Parker Hannifin

SciFlex® 140 NFF System
The SciFlex 140 is a proven bioprocessing platform for use in discovery to production scale disposable normal flow or dead-end filtration applications. SciLog’s patented technology within the SciFlex enables constant pressure or constant rate NFF via a pump PID loop including disposable inline pressure sensors. This technology is compatible with any commercially available filter (including depth, clarification, sterilization, pod, column etc.). The SciFlex embodies Open Architecture’s benefits, making it a built in failsafe for crucial operations, in which downtime is not an option. Two SciFlex skids that can accept similar but distinct manifolds can guarantee continuous operation.


  • Foot Print: 20” x 30”
  • Single use: yes
  • Flow Range: 0.25 – 80 L/min (depends on configuration)
  • Recommended Pump Head: Peristaltic, Diaphragm or Magnetic (depends on configuration)
  • Filter Type: Depth, Dead End, Sterilization, Capsule
  • Typical Hold-up Volume: < 100 mL (depends on configuration)
  • High Pressure Limit: 30 or 60 psi (depends on configuration)
  • Pressure Messuremant: 3 sensors included
  • Automated Pressure Control: yes
  • Input Voltage: 240

SciFlex® 150 TFF System
The SciFlex 150 is a single-use bioprocessing platform for the semi-automation, optimization, and documentation of TFF Applications. The system is ideal for Pilot level TFF processing and development. Via touch screen and pre-installed operational software users have the ability to create and execute discrete processing steps for concentration and diafiltration. User-selectable end points and alarms enable hands-free operation and ensure safe, consistent process performance.


  • Foot Print: 20” x 36”
  • Single use: yes
  • Flow range: 0.25 – 20 L/min (depends on configuration)
  • Recommended Pump Head: Peristaltic
  • Recommended Membrane Area: 0.1 – 2.5 m2 (depends on configuration)
  • Filter Type: Hollow Fiber or Flat Sheet
  • Typical Hold-up Volume < 200 mL (depends on configuration)
  • High Pressure Limits: 30 or 60 psi (depends on configuration)
  • Pressure Measurements: 3 Sensors Included
  • Automated TMP Control: Yes
  • Input Voltage: 240 
  • Pneumatic Requirements: 85 psi, dry, Air or Nitrogen

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