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ProteinMaker™ – High-throughput purification of proteins or antibodies

The ProteinMaker from Protein BioSolutions is an automated, powerful purification system for high-throuput parallel purification of up to 24 protein- or antibody-samples using cartridges or columns pre-packed with chromatographic media such as affinity-, IMAC-, IEX- or HIC-materials of various suppliers. This instrument allows multiple load, wash and elution buffers to be used in parallel along independent lines for up to 24 individual samples. This is accomplished by combining a x-y-z robotic system with 24 liquid dispensing manifolds controlled by an intuitive, easy-to-use software. As an option the system can be upgraded with a 24 channel UV-detector which allows to monitor the separation and will help you to identify the right fraction with your valuable protein. The separation can be performed using cartridges or columns of all major manufacturers.

The main application areas of the ProteinMaker are: 

  • Scouting of the optimal chromatographic media - screening of up to 24 different chromatographic media at the same time
  • Production of a few 100 mg protein for e.g. protein cristallography 
  • Multi column purification (e.g. affinity combined with IEX) for antibody production.

The ProteinMaker is suitable for sample volumes of few mL up to more than 1 L.

ProteinBioSolutions | Protein Maker | Parallel purification of up to 24 protein- / antibody-samples

Technical Service


During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.

Detailed information about our support options can be found here.

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Protein BioSolutions

Protein BioSolutions is a small but thriving company providing innovative and practical solutions to protein researchers. The company's flagship product, the Protein Maker, enables parallel protein purification of up to 24 proteins simultaneously on the preparative scale (~1-1000 mL). The Protein Maker provides next level efficiency for various applications including antibody production, structural biology, AAV processing, and gene therapy. If increasing protein purification throughput is needed, the Protein Maker is the answer. Protein BioSolutions is based in Gaithersburg, MD and serves customers all over the world.

More about Protein BioSolutions: www.pbiosolutions.com

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125 employees
10 locations in europe
32 years of experience