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Protein Fluidics
Pu•MA System™ 3D
Automated 3D cell-based Assays
The Pu•MA System 3D has been designed to automate assays for spheroids or organoids by maintaining the 3D cell model in a special designed flowchip to allow automated media or reagent exchanges.
- Automated workflow for complex assay protocols
- Protected sample chamber to prevent cell damage
- Automatic execution of media change, compound additions and supernatant sampling
- Small well with low reagent volume
- Compatible with high content imaging and plate reader systems
- Small footprint fits on bench and incubator
For even more comfort, explore the Pu•MA System EC with integrated temperature and CO2 control.
- 3D Cell Culture
- Automation
- Sample Processing
- Sample Preparation
- Stem Cell Cultivation
- Cell Culture
- Cell Biology
- Belgium
- Denmark
- Germany
- Finland
- France
- Luxembourg
- Netherlands
- Norway
- Austria
- Sweden
- Switzerland
Pu•MA System™ 3D – Assay automation for spheroids or organoids
The Pu•MA System 3D offers numerous advantages for cell cultivation and drug discovery. Firstly, it enables an automated workflow for complex protocols, ensuring high reproducibility of results. Secondly, the sample chamber protects cells from mechanical stress and guarantees gentle cell treatment. Additionally, the system performs automatic media changes, drug additions, and supernatant sampling. The small well format with a small sample volume allows for cost-efficient experimentation and is suitable for analyzing rare cells or limited samples. The system is also compatible with high-content imaging and plate readers and features a space-saving design for laboratory and incubator use. The intuitive touchscreen interface facilitates operation and enables quick familiarization with the system.
The Pu•MA System 3D is perfectly suited for a broad range of applications, including toxicology, metabolism, neuroscience, and oncology. The automated sequential drug addition and in situ imaging and sampling make the system particularly effective in oncology and neuroscience. In toxicology, the system can be used for toxicity testing in spheroids with in situ imaging. In metabolism, it can perform single-spheroid assays and subsequent metabolomics analyses.
With the Pu•MA System 3D, you can achieve precise control and automation of 3D cell assays, allowing you to program complex protocols and increase the reproducibility of results. The use of the Pu•MA System 3D is an effective and efficient way to automate your 3D assays and accelerate your research.
Applications:
- Toxicology: Toxicity testing in spheroids with in situ imaging
- Metabolism: Pu•MA System 3D for single spheroids assays and downstream metabolomics
- Neuroscience: Phenotypic response to sequential drug addition and analysis in neurospheroids
- Oncology: Automated organoid assays, sequential drug additions, in situ sampling and in situ imaging
Automate your assay – not only for single organoids
Example for applications
Protein Fluidics | Pu•MA System 3D | Automated 3D cell-based Assays
Technical data
| Performance | 8 - 32 samples per run 1 - 5 days processing time 10 - 20 µl reagent volume |
| Operating Conditions | Ambient temperature: 20 - 40 °C Relative humidiy: 15-95 % (non condensing) |
| Software | Touchscreen driven interface Pu•MA Software |
| connections | 2x USB 2.0 Port (front) 1x RS-232 9 pin serial port (rear) |
| Electrical Requirements | Power requirements: 12 VDC input voltage 110 - 240 VAC at 50-60 Hz 3,3 A current 30 W |
| Clearance | 15,2 cm from all sites (6 in) |
| Physical Dimensions | Width: 305 mm (12 in) Depth: 355 mm (14 in) Height: 203 mm (8 in) Weight: 11,4 kg (25 lbs) |
Consumables
| PF-7000-0053 | Membrane |
| PF-7000-0081 | 3D Cell Flowchips (4) |
| PF-7000-0082 | 3D Cell Flowchips (12) |
Technical Service
During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.
Detailed information about our support options can be found here.
The privately held company Protein Fluidics Inc. is located in the San Francisco Bay Area. The company is commercializing assay automation platforms using novel microfluidic technologies to accelerate data driven decisions in the Life Sciences. It provides scientists with the latest automation tools to help with the next breakthrough discovery in oncology, diagnostics, and more. The Pu•MA System 3D for your 3D cell models, organoids or spheroids, maintains the cells in our specially designed flowchips to allow for easy media, metabolite or reagent exchanges for your oncology, toxicity, or metabolomics research.
More about Protein Fluidics: https://proteinfluidics.com
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