RASTRUM™

Inventia Life Science

Advanced creation of 3D cell models

Easily produce reproducible, high-quality and disease-relevant 3D cultures with RASTRUM™. The platform is designed to support advanced 3D cell culture applications in drug discovery, biomedical research, and 3D cell biology. By creating models that more accurately mimic human tissues, RASTRUM accelerates the development of physiologically relevant cell cultures.

Key features

  • Easy-to-use
  • Intuitive user experience, no coding required
  • Streamlined workflow and setup for efficiency and ease
  • Gentle on cells, supporting sensitive cell types
  • Compact benchtop design
  • Drop-on-demand printing technology
  • Seamless integration of cell models into your existing workflows
  • Off-the-shelve consumables

Sales in

Austria, Belgium, Denmark, Finland, France, Germany, Ireland, Luxembourg, Norway, Slovenia, Sweden, Switzerland, The Netherlands, United Kingdom

Novel solution for creating 3D cell models

RASTRUM is designed to support advanced 3D cell culture applications in drug discovery, biomedical research, and 3D cell biology. The platform provides researchers with a precise and efficient way to generate robust, reproducible 3D cell models that reflect the complexity of human tissues. Its proprietary drop-on-demand bioprinting approach enables rapid, consistent formation of physiologically relevant cell environments.

The RASTRUM platform:

  • Minimises hands-on steps and standardises model creation to improve workflow efficiency and experimental reproducibility
  • Enables teams to confidently scale 3D culture work, from early-stage research to advanced applications
  • Provides a reliable foundation for disease modelling, drug screening, and regenerative medicine studies
  • Supports more predictive and translatable scientific outcomes

A complete benchtop solution:

  • The intuitive cloud-based software simplifies printing parameters and 3D architecture design.
  • Drop-on-demand bioprinting technology enables consistent and reproducible production of advanced cell models in a multi-well plate at scale.
  • Homogeneous distribution within the droplet enables high precision and speed, along with reproducibility and scalability.
  • The universal print deck allows printing in 24, 96 and 384-well plates.
  • Integrated Dual HEPA filters maintain a sterile and safe environment to protect cells from contamination.

Preserving 3D integrity – RASTRUM’s inert base layer, which coats the bottom of the well, prevents cells from migrating towards plastic surfaces, where they attach and lose their 3D characteristics. This innovation preserves the integrity of the 3D microenvironment, preventing the formation of 2D monolayers and enabling more physiologically relevant experiments.

The RASTRUM platform workflow

The cloud-based guided experimental design allows you to develop your 3D model from start to finish in 5 steps:

  1. Select your matrix from a large library of different matrices to mimic your individual tissue microenvironment.
  2. Select your model architecture by choosing the structure and cell model that best meet experimental needs.
  3. Follow a simple protocol to prepare your cells.
  4. Generate your 3D cell model using RASTRUM’s drop-on-demand bioprinting technology.
  5. Grow your cell model and integrate your analysis with existing downstream workflows and readouts.

Different cell model architectures allow you to cover a range of applications, including imaging, screening and cell extraction. These flexible architectures can be seamlessly integrated into various well plate formats, trans-well inserts or cover slips.

Downloads

Getting started with the RASTRUM platform

Learn more about the RASTRUM workflow and get started with the production of 3D cell models.

RASTRUM technology overview

A detailed description of the RASTRUM technology

RASTRUM Features and Specifications

Obtain more information on the features and technical specifications of the instrument

Technical data

PRINTING SPECIFICATIONS
Minimum drop volume 15 nl
Minimum drop diameter 150 μm
Minimum layer thickness 50 μm
Active printing nozzles 8
Drop placement resolution 20 μm
Maximum print frequency 1,000 drops per second (1,000 Hz)
Typical print frequency 300 drops per second (300 Hz)
Substrate SBS-standard micro plates: 24, 96, 384 (custom fixtures on request)
OPERATING ENVIRONMENT
Electrical Input: 100-240VAC, 50/60Hz, Output: 24VDC, 6.67A
Weight Approx. 50 kg (total)
Unit dimensions (D × W × H) 589,5 × 532,2 × 493 mm
Air supply Minimum: 300 kPa (3 bar), Maximum: 800 kPa (8 bar)
Mini air compressor (optional) 240V AC, 300 kPa (3 bar) maximum air pressure
Laminar Air Filter Medical grade class H14 HEPA filters
Cleaning Replace filter every 2 years
PC & SOFTWARE
Supplied PC Microsoft 11 Windows Pro 64-bit
Connectivity cable USB-A to USB-B
Supported operating system Windows 11