Bringing advanced Raman spectroscopy to real-time bioprocess monitoring
Modern bioprocessing demands accuracy, consistency, and more profound process understanding, whether working with fermentation, cell culture, or continuous production. To support these challenges and further strengthen our Process Analytical Technology (PAT) offering, I&L Biosystems has entered a new strategic partnership with Renishaw, a leading UK-based technology company known for its expertise in precision measurement and high-performance optical spectroscopy.
Introducing Renishaw
Renishaw is a global engineering company specialising in precision measurement, motion control, industrial automation, and calibration technologies. Its Spectroscopy Product Division develops a comprehensive portfolio of advanced optical spectroscopy systems designed to deliver reliable, high-resolution data across research and industrial environments.
Among these solutions is the Virsa™ Raman Analyser: Renishaw’s dedicated platform for in-line and in-situ Raman spectroscopy in bioprocessing. Supported by a global network of subsidiaries and distributors, Renishaw ensures robust customer service, technical support, and long-term reliability for laboratories and production facilities worldwide.
Virsa™ Raman Analyser: Real-time insights for upstream and downstream processes
The Virsa™ Raman Analyser enables non-destructive, real-time monitoring of substrates, metabolites, and media components directly inside bioreactors. Designed for aqueous cultivation and living systems, it accurately measures concentrations of key analytes, such as glucose and lactate, without disrupting the process.
Key advantages include:
- Exceptional sensitivity enabling shorter measurement times.
- Option to use two laser wavelengths for analysing a broad range of samples.
- Compatible with both small single-use bioreactors and large-scale continuous production setups.
- Integrated spectral calibration within the probe, eliminating the need for external reference checks.
- Support available through local service engineers and training resources.
- A secondary stand-by laser ensures continued operation when the primary laser reaches the end of its lifetime.
The Virsa system offers complete transferability across scales and supports Quality by Design (QbD) strategies by coupling powerful predictive modelling with Renishaw’s WiRE™ software. In both upstream and downstream workflows, Raman spectroscopy helps streamline process control, reduce reliance on offline analytics such as HPLC, and enhance overall process robustness.
Supply and support by I&L Biosystems
I&L Biosystems is now the official distributor for Renishaw’s Virsa Raman Analyser for bioprocess applications across Germany, Austria, Switzerland, France, Ireland, Benelux, and the Nordic countries. Alongside product supply and logistics, we provide comprehensive technical service and application support, ensuring smooth implementation and long-term performance of your Virsa systems.
Downloads
Virsa Raman Analyser Brochure
Virsa user guide
Interested in learning more?
If you’d like to explore how Raman spectroscopy could support your bioprocess development or production strategy, our team will be pleased to advise.