Key features
- Photometric measurement
- High sample capacity, up to 126 samples at once with continuous loading
- Measurement of up to 28 parameter in parallel (2-40 µl sample/parameter)
- Monitoring of mammalian, bacterial and yeast culture systems
- Automated daily maintenance
- Freely programmable automated on-board sample dilution
Sales in
Austria, Belgium, Denmark, Finland, France, Germany, Ireland, Italy, Luxembourg, Norway, Sweden, Switzerland, The Netherlands, United Kingdom
Cedex® Bio HT – Bioanalyzer for bioprocess control
The Cedex® Bio HT Analyzer is a multi-analyser for monitoring bioprocesses and fermentations. The wide range of measurable parameters allows the Cedex® Bio HT Analyzer to monitor the production and to develop and optimise growth conditions for mammalian, bacteria, and yeast culture systems. Substrates, metabolites, and products are measured photometrically by the Cedex Bio HT Analyzer, which is recommended for high throughput screening. The Cedex Bio HT Analyzer processes numerous samples simultaneously with minimal manual intervention.
The 96-well upgrade kit allows for the use of 96-well plates for a total capacity of up to 96 + 30 samples. Automated sample dilution saves time and ensures high accuracy. For process optimisation, the full automation of the Cedex® Bio HT also allows online integration with other automated systems.
Are you interested in automating the data handling of your Cedex Bio HT Analyzer?
Then, look at Sm@rtLine Data Cockpit (SDC) from our partner AGU. SDC is a middleware for central data handling in production, development, and research. It enables the connection of the Cedex Bio HT Analyzer (and many more analysers) to your LIMS system.
Contact us to figure out if SDC is the solution to your requirements.
Downloads
Cedex Bio Family Brochure
Learn more about the Cedex Bio family and how these devices will help you control your bioprocess.
Cedex Bio Assay menu and test details
Discover all assays for the Cedex Bio and Bio HT instruments, including their test ranges and specifications.
Cedex® Bio HT Analyzer Multiwell Upgrade
It presents the Cedex Bio HT Analyzer Multiwell Upgrade, enabling high-throughput automated measurement on 24-, 48-, and 96-well plates to reduce hands-on time, human error, and accelerate bioprocess feedback loops.
Use Case: A Smart Path for Novel Biologics
This use case describes how the pRED implemented automated microbioreactors and Cedex Bio HT analyzers to process up to 250 samples daily, increasing fermentation throughput 4–5× without additional staff.
Optimising bioprocess development with real-time high-throughput analytics
The article explains how Roche’s Cedex Bio Analyzer platform enables real-time, high-throughput analytics to drive data-driven optimization across early-stage bioprocess development.
Technical data
| Method of Measurement | Photometric |
| Test Throughput (Theoretical Max) | 150 – 300 tests/hour |
| Reagent capacity | 32 slots in 8 racks on board |
| Programmable Parameters | yes |
| Sample Types | mammalian cell culture |
| microbial fermentation | |
| yeast cell fermentation | |
| Sample Input | Up to 90 sample tubes (six 15-sample racks) |
| If using 96-well plate + two 15-sample racks, up to 126 samples | |
| Priority sampling available | |
| Barcode reading | |
| 96 well-plate upgrade kit (also offers possibility to use 24- and 48-well plates) | |
| Sample Volume | 2-20 μL sample consumption per test |
| Sample Container Types | Sampling tubes: 5-10 mL; 16 x 100; 16 x 75; 13 x 100; 13 x 75 mm |
| Standard cup: 1.5 mL Micro | |
| Micro cup: 650 μL | |
| Cup on tube definable | |
| Standard well plates (24-, 48-, 96-well) | |
| Minimum Sample Volume | 100 μL for several tests |
| Cuvette capacity | 1000 |
| pre-dilution | Freely adjustable |
| Rerun (automatic dilution) | re-run with automatic dilutions |
| Sample Barcode Types | Code 128, Codabar, Code 2 of 5 interleaved, code 39 |
| Sample cooling | yes |
| System Interfaces | RS232 serial interface for HOST connection, Ethernet for remote access |
| Connectivity to a network for Active Directory authentication via TCP/IP protocols | |
| Online integration with automated systems (e.g. Flownamics systems) | |
| Operating Conditions | Ambient temperature: 15 – 32°C |
| Ambient humidity: 30 – 80% (RH, without condensation) | |
| Water purity: Reagent grad NCCLS Typ I | |
| Water consumption: 2 L/day – connection to water supply possible (optional) | |
| Waste: Separate container – connection to sink possible | |
| Control Unit | HP workstation running Windows 10, Intel Core i5 with 32 GB RAM |
| Dual 500 GB hard drives, DVDRW drive, Ethernet | |
| Dual 512 GB SSD Solid State Memory, Ethernet | |
| Electrical Requirements | Power requirements: 100 – 125 V and 200 – 240 V |
| Consumption: 1200 VA | |
| Frequency: 50 Hz oder 60 Hz | |
| Physical Dimensions | Width: 1350 mm |
| Depth: 660 mm | |
| Height: 750 mm | |
| Weight: 198 kg (436 lbs) | |
| Weight (unpacked instrument only): 184 kg (406 lbs) | |
| Certificates | CE, UL, C-UL |
