Optimization of immune and stem cells
Manufacturer: XCell Biosciences
The human body exhibits diverse microenvironments that influence the behaviour and molecular profiles of cells. Tissues and organs function at a much lower oxygen level and various pressures than a standard incubator provide. Especially primary cells like immune cells/iPSCs/CTCs are difficult to handle in standard incubators: survival is minimal if any, expansion take a long time and often resulting in deviated phenotype expression.
The innovative AVATAR™ Cell Control System by Xcell Biosciences is the first commercially available cell culture system capable of reproducing in vivo microenvironments found within the human body, providing physiological pressures and oxygen states to the cell cultures and therefore reliable results.
The AVATAR™ optimizes growth, functionality and/or phenotype of interest.
Accurate and stabile control of pressure and oxygen levels
• Pressure levels: from 0 psi to 5 psi
• Oxygen levels: from 0.1 % to 20 %
Applications and examples
• Culture your cells under more physiologically accurate conditions
Achievement of more realistic scientific results
• Control your cell destiny
Reprograming / Maintenance of iPSCs
Differentiation from iPSCs to neuronal precursor cells
Differentiation from iPSCs to cardiomyocytes
Promotion of target protein expression profiles
• Expand primary cells
T-cells and NK-cells
2D and 3D organoids
• Improve transfection efficiency
Better regeneration of transfected cells
– You control your cells. Not the other way around. –