Fluxion Biosciences
BioFlux™ 1000Z Live Cell Imaging System
Live cell assays under shear flow
The BioFlux 1000Z has been developed to perform flow-based assays automatically at high throughput rates. The BioFlux 1000Z consists of the BioFlux controller and a Zeiss microscope. The screw cap of the BioFlux Interface has been replaced by a faster clip cap on the BF1000Z and there is a comprehensive integrated flow control and analysis package.
- Up to 96 flow experiments in parallel
- Precise shear force control (0.2 - 200 dyne)
- Pulsative flow up to 75 x / min
- Including Zeiss microscope with individual equipment
- Software for automatic flow control and automatic image evaluation
- Applications: Platelet aggregation, biofilm, cell adhesion...
- 3D Cell Culture
- Bacteria Cultivation
- Microscopy
- Cell Culture
- Microbiology
- Cell Biology
- Belgium
- Denmark
- Germany
- Finland
- France
- Luxembourg
- Netherlands
- Norway
- Austria
- Sweden
- Switzerland
BioFlux™ 1000Z – Live Cell Imaging System
The BioFlux™ 1000 system is designed for automated live cell imaging analysis under physiological and pathophysiological flow conditions (from 0.2 - 200dyne). The applications are versatile and range from analysis of platelet aggregation, cell adhesion, migration, transmigration, wound healing, stem cell differentiation to biofilm analysis, inhibition studies and host-pathogen interactions.
The use of microtiter plates with integrated microfluidics combines the simplicity and high throughput of corrugated plates with the quality and relevance of flow experiments. Thus it is possible to perform up to 96 live cell assays under controlled flow conditions in parallel.
In order to ensure the best possible optical properties, the bottom of the microtiter plates is made of optical glass. Furthermore, the BioFlux1000 instrument consists of the classic BioFlux instrument together with an automatic inverse Zeis microscope. Both systems are optimally matched to each other. This enables faster sample and experiment setup and automated data analysis. This allows fast and reproducible experiments even with high sample volumes and sensitive samples.
Fluxion Bioflux Biofilm system introduction
Fluxion Bioflux Live Cell Imaging system Plates
Technical data
Flow control | 0.2 - 200 dyne |
Temperature control | RT + 50°C |
Microtiterplate | SBS Standard, sterile, with PDMS channels and glass bottom |
Microtiter plate format | 6-well for up to 3 experiments (1 inputs / channel) |
24-well for up to 8 experiments (2 inputs / channel) | |
48-well for up to 24 experiments (1 input / channel) | |
Throughput | Up to 24 experiments in parallel with adapter up to 96 experiments |
Dimension observation channel | 350 µm x 70 µm (w x h) |
BioFlux Controller dimension | 30 x 33 x 23 cm |
Weight Bioflux Controller | approx. 17 kg |
Mikroscope | Zeis Z1 - individually equipped |
Software | Montage, combines Flow and Microscope control and Data analysis |
Downloads
Brochures
Manuals
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BiofilmGrowth316.14 KB
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Cancer cell adhesion assay557.52 KB
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Cellular Monolayer in microfluidic channels1.81 MB
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Cell rolling357.23 KB
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Host Pathogen Interactions1.93 MB
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Matrigel in Microfluidic channels95.77 KB
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Platelet Adhesion and Aggregation Assay643.01 KB
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Platelet Adhesion dose rsponsen708.04 KB
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Pulsatile Flow Module - Tech Note (1075-01)177.95 KB
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StemCell Differentiation2.92 MB
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Transmigration711.01 KB
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Wound Healing1.11 MB
Consumables
FL-910-0110-5Pack | BioFlux 1000z 6-well plate 0-20 dyn |
FL-910-0048-5Pack | BioFlux 1000z 48-well plates, high shear, 0-200 dyn |
FL-910-0047-5Pack | BioFlux 1000z 48-well plates, low shear, 0-20 dyn |
FL-910-0120-5Pack | BioFlux 1000z 48-well custom substrate plate |
FL-910-0051-5Pack | BioFlux 1000z 24-well plate 0-20 dyn |
FL-910-0121-5Pack | BioFlux 1000z 48-well 0-20 dyn PDMS bottom plates |
FL-910-0145-5Pack | BioFlux 1000z 24-well 0-20 dyn PDMS bottom plates |
Accessories
FL-940-0020 | BioFlux Pulsatile Flow Module |
FL-200-0031 | Harness, from controller to vapor trap (old style vapor trap) |
FL-200-0032 | Harness, from vapor (old style) trap to 48-well interface |
FL-200-0033 | Harness, from vapor trap to 24-well interface (old style) |
FL-300-0008 | Filter 0.2 uM luer lock for inside BF controller and vapor trap |
FL-800-0068 | Gasket for 24-well interface |
FL-800-0069 | Gasket for 48-well interface |
FL-910-0017 | Qty 16 0.2 uM replacement filters for BioFlux controller |
Further accessories on request
Technical Service
During our business hours, our free telephone support will be glad to assist you in case of any questions. Our Technicians take care of the delivery and installation of original spare parts of the highest quality as well as certified testing, measuring, and control equipment. Our maintenance according to manufacturer specifications includes functional tests, cleaning, accuracy testing with calibration as well as a detailed report. In addition, our maintenance contracts protect your investments and reduce the total cost of ownership.
Detailed information about our support options can be found here.
Fluxion Biosciences is located in California and delivers advanced solutions that automate complex cell-based and cell-free assays. Products include ERASE-Seq for NGS analysis of cancer from a "liquid biopsy"blood sample, IsoFlux for circulating tumor cell analysis, BioFlux for functional analysis of cellular interactions, and the IonFlux automated patch clamp system. Hundreds of labs worldwide rely on Fluxion's solutions to research novel biology, accelerate drug discovery, and tailor therapies based on patient-specific biomarkers.
More about Fluxion Biosciences: www.fluxionbio.com
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