Sepragen Superflo Chromatography column
Sepragen SuperFlo production Chromatography column
Sepragen SuperFlo production Chromatography column

SuperFlo® production columns

Low pressure production chromatograpy columns

Manufacturer: Sepragen® Corporation

SuperFlo® Radial Flow Chromatography Columns are redefining the possibilities in low pressure, preparative liquid chromatography. Due to the unique design, the column offers a significantly larger sample inlet area, which results in lower linear velocities, even at high total flow rates.The production columns are available from 5-500 L made from acrylic or stainless steel.

  • Offers high flow rates
  • Low working backpressures
  • Fast separations
  • Ideal for antibody purification
  • Easy and fast to pack
  • Worldwide in use for plasma fractionation
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  • SuperFlo® production columns

    The SuperFlo® column consists of two concentric porous cylinders, creating a space. This area between the frits is the column bed and this is packed with the chromatographic resin.The eluent/sample enters at the top of the column, the top lid acts as a distribution head and directs the sample into the gap between the outer column body and the outer frit. It distributes over the whole height of the column and flows horizontal from the outer frit to the inner core. From the gap between the inner frit and the collector rod (spacer in the centre of the column) the eluent leaves through the outlet at the bottom of the column. The effective bed height of the column is the distance between inner and outer frit.


    The intrinsic design of the SuperFlo® column has a significantly larger surface area than a tradtional  axial column, therefore even at high flow rates the linear velocity is in a range which allows for the required interaction between sample and resin. SuperFlo® allows to make your separation faster and in certain cases you can save expensive resin (e.g. Protein G) because you can make 2 runs in the same time - means you can reduce the size of the column by 50%. The investment into a SuperFlo® column will be compensated by the savings in resin costs after the first column packing.

    Technical data


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    Please find further information about our Technical Service here.

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    James Newton|

    Product Specialist

    +44 7366995053

    Pira Ragulan|

    Product Specialist for UK

    +44 (0) 741 316 3421

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